Virginia Newborn Dried Blood-Spot Screening Services screens infants born in the Commonwealth for selected heritable disorders and genetic diseases, which are identified through newborn dried blood-spot screening tests. Effective March 2006, the disorders were expanded to include the additional 17 disorders recommended by the American College of Medical Genetics in its report, Newborn Screening: Toward a Uniform Screening Panel and System. This expansion brings the number of disorders screened to the recommended 28. Infants are generally screened within the first few days after birth, but may receive screening services until they reach 6 months of age. Due to the state laboratories procedures and cutoff levels, which are based on normal infants hematocrit, screening for infants 6 months and older must be conducted by laboratories that conduct testing for children and adults. The disorders screened are listed below. 1. Argininosuccinic acidemia (ASA); 2. Beta-Ketothiolase deficiency (�KT); 3. Biotinidase deficiency (BIOT); 4. Carnitine uptake defect (CUD); 5. Citrullinemia (CIT); 6. Congenital adrenal hyperplasia (CAH); 7. Congenital hypothyroidism (CH); 8. Cystic fibrosis (CF); 9. Galactosemia (GALT); 10. Glutaric acidemia type I (GA I); 11. Hemoglobin Sickle/Beta-thalassemia (Hb S/�Th); 12. Hemoglobin Sickle/C disease (Hb S/C); 13. Homocystinuria (HCY); 14. Isovaleric acidemia (IVA); 15. Long chain hydroxyacyl-CoA dehydrogenase deficiency (LCHAD); 16. Maple syrup urine disease (MSUD); 17. Medium-chain acyl-CoA dehydrogenase deficiency (MCAD); 18. Methylmalonic acidemia (mutase deficiency) (MUT); 19. Methylmalonic acidemia (Cbl A,B); 20. Multiple carboxylase deficiency (MCD); 21. Phenylketonuria (PKU); 22. Propionic acidemia (PROP); 23. Sickle cell anemia (Hb SS disease) (Hb SS); 24. Tyrosinemia type I (TYR I); 25. Trifunctional protein deficiency (TFP); 26. Very long-chain acyl-CoA dehydrogenase deficiency (VLCAD); 27. 3-hydroxy 3-methyl glutaric aciduria (HMG), and 28. 3-Methylcrotonyl-CoA carboxylase deficiency (3MCC).